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Only 1 retrospective cohort study was included, with the remaining articles consisting of case reports and case series.
To each group, test articles consisting of PBS, rAAV2/EV (vector with no transgene) or rAAV2/mCysC (vector encoding mouse cysC) were administered by intra-articular route and all opposing sham knee joints received PBS (700 μl/joint for all treatments).
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To a large degree, the articles consist of aggregation: a Bustle writer finds a piece of news that interests her — from the Times, or from a blog she likes — and summarizes it for Bustle's readers, perhaps making its contents into a list, or collecting some related tweets.
The selected articles consisted of five randomised controlled trials, three prospective studies, four systematic reviews, three meta-analyses and six retrospective studies (Fig. 1).
These articles consist of revision, updating, and integration of articles on standards for clinical trials in male and female sexual dysfunction from the 2010 International Consultation on Sexual Medicine developed by the authors as part of the 2015 International Consultation on Sexual Medicine.
The final set of included qualitative research articles consisted of 1,255 papers.
The top 50 articles consisted of 21 clinical trials and 29 observational studies.
Ten articles consisted of qualitative studies; three of quantitative descriptive studies, and one article used a mixed method approach.
Of the 207 full text articles reviewed, 23 of the identified articles consisted of epidemiological information (overview of the 23 articles available on request).
The final set of 28 included articles consisted of 27 laboratory studies and 1 field study (see Online Resource 2 for the references of all included studies).
The 99 articles consisted of 87 instruments for RCTs of conventional medications and 12 guidance documents written to guide reporting of an RCT and/or discussed the importance of quality assessment of RCTs of conventional medicine.
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