Exact(31)
VraE did not significantly affect the development or severity of arthritis (data not shown).
Inoculation of the ecsA::intron mutant and wild-type Newman strains supported the results obtained in the infection with ΔecsAB mutant and wild-type LS-1 strains with respect to weight loss and frequency of arthritis (data not shown).
GST immunization did not induce apparent arthritis (data not shown).
NG and MT provided the rheumatoid arthritis data.
Clinical arthritis data were analysed by two-way ANOVA.
Other clinical parameters were not associated with the development of arthritis (data not shown).
Similar(29)
Admire was invoked using default parameters and the following genomic regions and gene sets: 2-kB promoter regions and positional gene sets for the rheumatic arthritis (RA) data and 5- and 10-kB genomic tiling regions for the atrial fibrillation (AF) data.
Given the recent demonstration of anti-inflammatory properties of GSK3 inhibitors, and the use of low dose methotrexate as the gold standard treatment for rheumatoid arthritis, our data raise several interesting possibilities for the use of these inhibitors in the clinic.
Whilst not routinely used to manage psoriatic arthritis limited data indicates it is effective.
Finally, severe vasculitis was seen in the vertebrae of the oldest IIJ arthritis mouse (data not shown).
First, we immunized DBA/1 mice with each APL alone, and confirmed that no overt arthritis developed (data not shown).
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