Sentence examples for arteries suggested from inspiring English sources

Roger Illingworth, a professor emeritus at Oregon Health & Science University who helped write the national guidelines for cholesterol-lowering drugs, says the fact that patients in Japan with CETP-lowering mutations still had clogged arteries suggested the drug would not work.

Consistent with this observation, immunostaining analysis of injured femoral arteries suggested the presence of similar numbers of CD3-positive T lymphocytes in E2- and placebo-treated mice.

The fact that periodontopathic bacteria were detected from atheromatous plaques of coronary arteries suggested that periodontal bacteria such as Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans invade endothelial cells and induce chronic vascular inflammation [ 19].

However, the same authors found a significantly smaller intracerebral arterial constriction compared with the constriction of extracerebral arteries – suggesting a primarily peripheral site of action for triptans.

A subsequent coronary angiogram revealed patent coronary arteries, suggesting that the mechanism was vasospasm.

In unstable angina neutrophilic inflammation is present in the coronary arteries, suggesting that acute inflammation has a role in this process [58, 70].

Interestingly, glibenclamide could partially inhibit PACAP induced vasodilation in cerebral, coronary and pulmonary arteries, suggesting that PACAP may also activate KATP channels [44, 45].

Coronary angiography performed a few weeks later showed normal coronary arteries, suggesting involvement of the coronary microcirculation, which was consistent with CV-related heart involvement.

COX-1 was found in the endothelium in healthy and in atherosclerotic vessels.Conclusions : the expression of COX-2 by inflammatory and vascular cells in atherosclerotic arteries suggests that products of this enzyme may be important in the pathogenesis of atherosclerosis.

However, apigenin did not affect the 0.1 μM phorbol 12,13-dibutyrate-induced 12,13-dibutyrate-induced 12,13-dibutyrate-inducedration range that relaxed the phenylephrine-contractionarterIC50=34.6±1.2ng that apigenin did not influence protein kinase C-mediated contractile mechanisms in rat aorta.

This augmented drug distribution away from the release source, down the axis of the left ventricle, and selectively toward the left heart follows the direction of capillary perfusion away from the anterior descending and circumflex arteries, suggesting a role for the coronary circulation in determining local drug deposition and clearance.