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Steady-state O PET with arterial sampling was performed to measure CBF, cerebral metabolic rate of oxygen (CMRO2), oxygen extraction ratio (OEF) and cerebral blood volume (CBV) [ 2].
Arterial sampling was performed twice, first while patients were untreated during a current depressive episode and then following 12 weeks treatment with an SSRI.
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Dynamic (R -[11C]verapamil scans with aR -[11C]verapamilwere performed twice on the scansday in 13 healthy controls.
[C]PIB studies with arterial sampling were performed in eight AD patients and eight healthy controls.
Repeated arterial blood sampling was performed on the arterial side after the blood had passed the detector.
Radial arterial blood sampling was performed throughout the 90-min scan.
Arterial blood sampling was performed continuously for the first 10 min of scanning.
Repeat research studies with arterial blood sampling was performed after approximately 12 weeks of therapy.
Although arterial blood sampling was performed in all subjects, due to technical reasons, plasma input data were not available for one control (retest) and two AD patients (both test and retest) scans.
Room air arterial blood gas sampling was performed according to standard guidelines.
Furthermore, coronary sinus blood sampling was performed 15 min after reperfusion simultaneously with arterial blood sampling.
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