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In October 2006, a biorepository of plasma and DNA samples was initiated by recruiting patients referred for lower extremity arterial evaluation to the Mayo Clinic's non-invasive vascular laboratory and individuals referred to the stress ECG laboratory to screen for coronary artery disease.
Arterial evaluation for AVF should consider pulse examination, differential pressure, palmar arch patency and arterial size.
PAD patients were identified from individuals referred to the non-invasive vascular laboratory for lower extremity arterial evaluation.
In order to complete the arterial evaluation, the arterial anatomy must be imaged in order to determine if it is suitable.
All patients underwent preoperative peripheral arterial evaluation with physical examination, measurement of ankle brachial pressure index (ABI), and either digital subtraction angiography or computed tomography angiography.
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We evaluated whether simplification of the Rapid Arterial oCclusion Evaluation (RACE) scale, a 5-item scale previously validated in the field, could maintain its high performance to identify patients with LVO.
As pulse waves travel faster in stiffer arteries, PWV measurement is consequently the best surrogate for arterial stiffness evaluation in everyday practice.
For this purpose it appears more appropriate an approach based on the arterial elastance evaluation as calculated by ratio between pulse pressure variation and stroke volume variation [ 23].
At odds with those studies, ours did not rely on the direct measure of pulse wave velocity (PWV) by applanation tonometry (the real gold standard of arterial stiffness evaluation) but on the measure of central pressure augmentation (i.e. a proxy of PWV) using a more convenient and less operator-dependent oscillometric method.
Two hours later, echography and mean arterial pressure (MAP) evaluation were performed; blood samples and heart were then collected to evaluate biological parameters (lactate, troponin T, creatinine), inflammation, autophagy and total O-GlcNAcylation by western blot.
Arterial blood gas evaluation was also performed every 30 min after thrombolytic treatment, and then every 6 h up to stabilisation.
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