The phrase "artefacts are difficult to" is correct and usable in written English.
You can use it when discussing the challenges or complexities associated with artefacts in various contexts, such as archaeology, history, or data analysis.
Example: "In archaeology, artefacts are difficult to date accurately due to the various factors that can affect their preservation."
Alternatives: "artefacts pose challenges to" or "artefacts are hard to".
Importantly, resting state and grasping task fMRI data sets were analysed in an identical way but were never compared directly due to categorical differences in movement artefacts which are difficult to disentangle from differences in functional interactions in the cognitive states.
These non-random gene-level CNAs, which are difficult to explain as noises or artefacts, are more sensitively associated with invasive (group C) tumours than are infrequent chromosome-level changes.
Most of the applications of wavelet-based methods under survey are for defects which are difficult to be identified from pseudo defects like scale and other artefacts which are frequently observed in surfaces of slab, billet, plate and rod.
Previously, there were concerns that these dimers were merely an artefact of overexpression in transfectants, particularly as we and others have found that they are difficult to detect on JEG-3 choriocarcinoma cells 17, 19.
p. 18. "The unusually symmetric pairs of paralogs are difficult to individually validate statistically and can be readily explained by either the artefact of the unknown period of evolving as a single gene between the speciation and duplication events".
Unorthodox phylogenetic relationships based on mt genome data can be explained as artefacts due to e.g. incorrect rooting [ 32] or low signal-to-noise ratio [ 33], but are difficult to correct.
Moreover, EEG is affected by numerous artefacts [ 51] and their corrections (e.g., eye tracking for ocular movements [ 52]) can lead to even weightier methods that are difficult to implement in routine clinical practice.
Scientists have uncovered other evidence that suggests Neanderthals made Uluzzian tools and ornaments at sites in France, but at some of these, it is difficult to be sure that the artefacts are the work of Neanderthals.
Although there is also evidence that the degradation of other RNA occurs, it has been difficult to distinguish between (i) experimental artefacts, (ii) natural RNAs that are degradation products, and (iii) natural sRNAs that have a functional role.
Cardiac involvement is difficult to demonstrate due to motion artefact and blood pooling in addition to proximity of the spleen.
