"art domain" is a correct and usable phrase in written English.
It refers to the specific area or field within the larger category of art. This phrase can be used when discussing different types of art or when talking about the different areas within the arts. Example: "Her expertise lies in the art domain of sculpting, but she also dabbles in painting and drawing."
The ExoS ART domain construct ExoS233-453 inactiveive under these conditions.
We conclude that the core of the ExoS ART domain is competent for catalysis.
d Schematic representation of ExoS ART domain construct ExoS233-419 lacking the C-terminal LDLA-box containing fragment (green).
In the ExoS ART domain (gold), the C-terminal fragment (green) was replaced by that of Vis toxin (blue; PDB entry 4XZJ).
Here we present crystal structures of human 14-3-3β 14-3-3β 14-3-3β the ART domain of both ExoS and ExoT.
This was in line with our initial observation that expression of complex containing the full wild-type ExoS ART domain was toxic (Supplementary Methods).
Our crystal structures revealed an extensive interface between 14-3-3 14-3-3 14-3-3and ExotheRT domains.
The ADP-ribosyltransferase activity of ExoS and ExoT and their cellular toxicity are dependent upon association of the ART domains with 14-3-3 14-3-3 14-3-34 These are ubiquitous, abundant regulators of diverse signaling proteins, and act through hundreds of cellular targets.13,14
The ExoS233 419 constructs (ART domains with C-termini deleted) were co-expressed with 14-3-3β 14-3-3β 14-3-3βin T7E.press lysY (New England Biolabs) by inducolin with 1 mM IPTG for 3 h at 37 °C.
The ART domains of exotoxins S and T of P. aeruginosa are closely related, yet differ in specificity for target molecules.
For cued nouns, significant positive correlations were found between participants' semantic distance values and log-transformed CAQ scores in the science and visual art domains.
