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A comparison against several representative state-of-the-art consensus functions reveals that our proposals constitute an appealing alternative for conducting fuzzy consensus clustering, as they are capable of yielding high quality consensus partitions at a low computational cost.
Side-chain sampling increases the performance significantly to Z = 31.1 and levels out at around 10 resamples per model, surpassing even the state-of-the-art consensus Pcons.
By including Recon 2 as a point of reference, we can compare this state-of-the-art consensus network with other pathway databases.
Results were compared with Pcons (Larsson et al., 2009), a state-of-the-art consensus method, and EVFOLD-MQAP (Hopf et al., 2012), a predicted ranking based on satisfaction of unused constraints, predicted secondary structure and predicted lipid exposure agreement.
The side-chain resampling is able to improve side-chain packing for 96% of all models, and improve model selection by 24% as measured by the sum of the Z-score for the first-ranked model (from 25.0 to 31.1), even better than the state-of-the-art consensus method Pcons.
You don't make art by consensus".
Still, the art of consensus can sometimes slow women down and diminish their leadership credibility.
But you can't make a good piece of public art by consensus; it's just not possible.
If those who commission public art seek consensus and universal popularity, this means ignoring the really original ideas, and preferring drab third-rate art such as the giants kissing at St Pancras station in London.
You don't make art by consensus". I remember talking to a man who had been involved in racially integrating a North Carolina lunch counter as a youngster in the 1960s, who described the sense of "elation and celebration" as he took his seat under the Whites Only sign.
But, more seriously, says Mr Nilekani, his four years in government has taught him patience and the art of consensus building.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com