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Compound 9j induced cell apoptosis and arrested cell cycle at G1 phase in MCF-7 cells.
Compounds 17 and 26 arrested cell cycle and induced mitochondria-mediated apoptosis in cancer cells.
In particular, 5k induced H4IIE apoptosis, arrested cell cycle at the S phase.
Using this approach, EV acted as a dominant negative inhibitor of STAT5b phosphorylation, arrested cell proliferation, and induced massive apoptosis.
3-[E- 4-fluorostyryl)]-2-chloroquinoline (compound 7B) caused substantial DNA damage and arrested cell cycle in S phase.
Flow cytometric analysis showed appreciable number of both cell lines in early and late apoptotic stages and arrested cell cycle in the G1 phase by GNP-NKCT1.
Compound 18 potently inhibited BTK kinase Y223 auto-phosphorylation (EC50 < 100 nM), <span class="lh">arrested cell cycle in G0/G1 phase, and induced apoptosis in Ramos, MOLM13 and Pfeiffer cells.
9 also potently inhibited BTK Y223 auto-phosphorylation (EC50: <30 nM), <span class="lh">arrested cell cycle in G0/G1 phase and induced apoptosis in U2932 and Pfeiffer cells.
Chidamide arrested cell cycle in G2/M phase by up-regulating the acetylation of histone H3 and interfering phosphorylation of AKT protein.
Mutations in a novel Arabidopsis gene RUNKEL (RUK) result in cytokinesis defects caused by abnormal phragmoplast organization and arrested cell plate expansion.
The results indicated that RY10-4 suproliferationiferarrestedrrested cell cycle, induced apoptosis and inhibited invasion in MDA-MB-231 MDA-MB-231 MDA-MB-231st cancer cells.
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