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Critical investments like these are essential to arrest the progression of the disease and prevent loss of sight.
Several drugs designed to slow or arrest the progression of ADPKD have shown promise in preclinical models and clinical trials, including vasopressin receptor antagonists and somatostatin analogs.
"It's quite possible that early intervention could arrest the progression," said the lead author, Dr. Anil K. Lalwani, a professor of otolaryngology at Columbia University.
Additionally, cells have evolved complex signalling pathways to arrest the progression of the cell cycle in the presence of DNA damage, thereby providing increased time for repair and tolerance mechanisms to operate21 (Fig. 2c).
These results demonstrate the potential therapeutic effects of P1 to prevent and/or arrest the progression of hypoxia-induced PAH via NO/cGMP-dependent modulation of hemodynamic and vascular remodeling in the pulmonary circulation.
Preserving regional differences in nucleosome occupancy and dynamism would not be possible without agents that arrest the progression of remodeling.
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The Anecortave Acetate Risk Reduction Trial (AART) was designed to demonstrate that anecortave acetate suspension (15 mg or 30 mg) is safe and effective in arresting the progression of non-exudative (dry) AMD in patients who are at-risk for progressing to exudative (wet) AMD.
Fortunately, the antibiotics effective against tuberculosis are effective today in arresting the progression of the disease.
Collagen cross-linking, however, arrested the progression of the disease.
These results support the efficacy of the tested nicotine replacement gum in stain reduction, in arresting the progression of tooth stain and in shade lightening.
Arresting the progression of the disease with effective treatment at this stage, when the vision is not markedly damaged, would be desirable.
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CEO of Professional Science Editing for Scientists @ prosciediting.com