In summary, comparing the 44C and 65A arrays to the rest of the Drosophila CPR gene family, I conclude 1) that the greater variation in gene number detected by CAFÉ within these arrays is associated with paralog homogenization; and 2) that there can be pronounced biases as to which genes within arrays are susceptible to sequence homogenization.
MAP-2 immunostaining showed the linear and curvilinear arrays were associated with dendrites.
Redundancy in genotyping arrays is associated with higher costs per SNP, concomitant with lower numbers of SNPs able to be interrogated in a given area of the microarray.
These arrays are associated to more than 50 different expression profiling experiments that were analyzed via the EMMA [ 37, 38] software.
On the other hand, perimodiolar arrays were associated with increased scala vestibuli mislocation in the present study and in several others [ 26, 27].
Studies have indicated that thinner arrays are associated with lower postimplantation hearing thresholds in animal models [ 33], and thinner tips (250 350 μm) are associated with lower insertion forces during implantation [ 34].
Both of these arrays are associated with proteins, including heterochromatin protein 1 (HP1), which is the product of the Suppressor of variegation 205 [ Su var) 205] gene (James et al. 1989; Capkova Frydrykova et al. 2008).
A considerable number of "disorders of unstable repeat expansion" are characterized by a specific genotype-phenotype correlation, such that the longer repeat arrays are associated with an earlier age-at-onset and with more severe symptoms [ 37].
When Sputnik was applied to the masked clones, we found that 557 and 454 out of the 1695 repeat arrays were associated with tRNA SINEs and other repeats, respectively.
Almost two-thirds of the I-E arrays were associated with paired loci, i.e., two CRISPRs (one with inverted repeat sequences) flanking internalized cas genes, as often observed in Archaea [ 42].
