However, despite of several optimization steps, the rate of misidentification of oligonucleotides remained >1.8% in consecutive validation experiments using arrays representing the genetic diversity at three MLST loci.
While the latter have successfully industrialized the analysis of gene and protein expression, fluid cell membrane arrays represent the industrialization of membrane biology.
Custom intergenic tiling arrays representing the genome of S. pyogenes NZ131 (NCBI accession number: NC_011375) were designed to detect the expression of potential sRNAs.
Custom NimbleGen 4-plex arrays representing the 4,034 tentative unique genes were queried with RNA from eleven different biological states representing larvae, pupae, and midguts and associated fat bodies of unfed or fed adults.
Given these considerations, we thought it of interest to study the gene expression profile of DMH-induced colon tumours in rats with the 44K Agilent rat arrays, representing the whole rat genome.
We thus performed time-series global transcriptional analyses from spleens of mice infected with 17X and 17XL parasites on days 3, 4 and 5 p.i using commercially available arrays representing the complete mouse genome (Agilent Whole Mouse Genome G4122A).
Technical artefact is an issue because much of the evidence for wholesale transcription of the genome derives from tiling array technology, in which labelled cDNAs representing the transcriptome are hybridized to arrays representing the entire genome, and which is susceptible to false positives due to hybridization with imperfectly matched probes.
where the three-way array represents the model residual.
The trajectory of the model array represents the best fit to the observed pore water data (Figure 13).
