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Rocke and Durbin [ 52] concluded that the gene expression data measured by DNA micro-arrays or oligonucleotic arrays contains both additive and multiplicative error components.
Affymetrix GeneChip Human Gene 1.0 ST arrays contain both miRNA and mRNA probes and are capable of measuring about 20,000 mRNAs and 200 miRNAs.
Bipolar Electrode This consists in two electrode applicators or in a single array containing both the active and return electrodes.
In this study, we developed the NimbleGen array containing both gene-based and repeat junction-based probes for mapping of the hexaploid wheat genome.
The samples were hybridized on GeneChip Human Gene 1.0 ST Arrays containing both miRNA and mRNA probes (Affymetrix, USA) for 16 h at 45°C.
To test this, TTP expression was evaluated by immunohistochemistry using human tissue arrays containing cervical tissue sections from both normal and squamous cell carcinoma.
Subsequently, we used the Exon Array probeset annotation and retained only the genes where the Exon Array meta-probeset coordinates contained both the Illumina and U133 probesets.
It must be noted that the triple-negative subtype defined in our study contains both array-defined basal-like tumor and unclassified subtypes, since we have not performed immunohistochemical staining for HER1 and cytokeratin 5/6 [ 12].
Even extremely small arrays containing a few cells are of great importance for users.
Illumina™ arrays containing over 47,000 probes were used to study global transcriptional changes.
These expression studies have utilized arrays containing probe sets of up to 35,000 genes.
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