The protocol for integrating extrachromosomal arrays (for Figure 3B) was adapted from a protocol previously described (Mello and Fire 1995).
The Robust Multi-array Average (RMA) algorithm was adapted to normalize and summarize the intensities of probes into gene-level expression.
A DNA macroarray was adapted from a previously described array [ 21].
The focused array system that we used in this study was adapted from the system reported by Iyer et al. [ 38] and Wang et al. [ 14].
The data collector scheme was adapted to conform to an L9 34) orthogonal array.
Based on experiences from previous works with the POCI array (Potato Oligo Chip Initiative) [ 10], the database schema from this project was adapted for the OPTIMAS oligo chip.
Suffix arrays can be adapted to special needs in bioinformatics applications such as spaced and subset seeds in sequence homology search.
This means that surgical technique and electrode array design must be adapted to minimize trauma.
Thus, this remnant CRISPR array may have been adapted for regulation in 1/2a EGD-e and possibly other strains of the species.
