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In patients who have unambiguous red cell failure defined by macrocytic anaemia and reticulocytopenia and decreased or absent red cell precursors in the bone marrow, the differential diagnosis of pure red cell aplasia includes DBA and a diverse array of acquired disorders (Table I).
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The host in turn continuously deploys an array of innate and acquired cellular and humoral defences to prevent pneumococci from breaching tissue barriers.
The hallmark of human cancer is heterogeneity, reflecting the complexity and variability of the vast array of somatic mutations acquired during oncogenesis.
Furthermore, a more complete understanding of the full array of constitutive, and acquired, parameters in the reptilian immune system would allow for increased accuracy in diagnosing levels of pathogen exposure as well as host resistance in natural populations.
A sound knowledge of hypothalamic pituitary thyroid axis physiology and the factors governing TH action at a tissue/cellular level, coupled with an understanding of the diverse array of congenital and acquired conditions that can manifest with different TFT patterns, is crucial to establishing the correct diagnosis in patients presenting with anomalous TFTs.
In addition to KEGG reference lipid metabolic pathways, the Pathway database contains lipidomic, microarray, and protein array data acquired by member laboratories of the LIPID MAPS (Lipid Metabolites and Pathways Strategy) consortium.
After two washing steps, images of the arrays were acquired with the Agilent scanner and analyzed by using the Feature Extraction software (v9.1).
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