Your English writing platform
Free sign upSuggestions(1)
Exact(3)
PCA could be considered as a "black box" that extracts some hidden features in the input data array and calculate new output data array that describes substances.
Scanned images obtained by the Affymetrix GeneChip Operating Software (GCOS) v1.2 were used to extract raw signal intensity values per probe set on the array and calculate detection calls (absent, marginal, or present).
This random sampling was repeated 10,000 times to approximate the null odds ratio distribution of each term on the array and calculate the significance of observed methylation enrichment.
Similar(57)
The β values were calculated by subtracking background using negative control on the array and calculating the ratio of the methylated signal intensity to the sum of both methylated and unmethylated signals plus a constant of 100.
EASE performs a statistical analysis of gene categories in a gene list relative to all genes on the array and calculates a conservative variant of the standard Fisher exact probability called the EASE score.
This value is calculated by subtracting background hybridization levels obtained from negative control probes on the array and calculating the ratio of the fluorescent signal from the methylated allele (M) to the sum of the fluorescent signals from both unmethylated (U) and methylated alleles (|U|+|M|+100).
As before, we normalized the values in each of the six types of arrays and calculated their exact local Whittle estimators.
To select proteins that interact with total RNA or mRNAs, we retrieved background subtracted median signal intensities of both channels from five replicate arrays, and calculated percentile ranks from 0 to 1 for each channel and array (raw data is given in Dataset S2).
Fortunately, we can reduce the memory by only storing a small fraction of the O and S arrays, and calculating the rest on the fly.
The intensities of these control spots were used to normalize the whole array and to calculate a threshold value.
For each spike we calculated the median of ratios within each array and then calculated the median of these median ratios from the replicate arrays, obtaining one total measure of expression ratio for each spike.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com