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The serial arrangement of active segments has one contracting degree of freedom in the thickness direction of the dielectric EAP film layers.
The regular arrangement of active sites in MOFs was shown to provide their superior behavior in Pechmann and Knoevenagel condensation reaction, while higher porosity and concentration of mild Lewis acid centers allows the conversion of bulky substrates to desired products over MOFs in Beckmann rearrangement, Friedel Crafts acylation, and annulation reactions.
Both are assumed to strongly resemble the LDH·NADH·pyruvate species with regard to general structure (Kd values and arrangement of active site contacts).
In this framework, a small molecule can be considered a spatial arrangement of active chemical groups connected by inert bridging fragments.
This allowed us to examine the superficial patch system and the arrangement of active regions in OI response maps for evidence of lattice structure, pooled across several experimental animals.
In both species, the arrangement of active regions cannot be distinguished from the jittered hexagonal lattice model (PK S = 0.10 and PK S = 0.28 for cat and monkey, respectively) and differs significantly from the jittered square lattice model (PK S < 0.01 and PK S < 0.001 for cat and monkey, respectively).
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Both the arrangement of active-site residues and the architecture of the interface with Ub lead us to classify this domain as the founding member of a previously unknown class of deubiquitinating enzymes.
Therefore, Ire1 and SEN apparently cleave RNA using different arrangements of active site residues.
Stability often correlates with reduced conformational flexibility, however, and biochemists now appreciate that structural plasticity and dynamism can empower the evolution of function by providing access to different conformational states and unique arrangements of active site residues.
Additionally, we identified xylose as a mixed-inhibitor of CBP activity, possibly due to the arrangement of enzyme active sites in the CBP homodimer.
The TR from P. falciparum (PfTR) represents a distinct type of high- Mr TR (type II) because instead of using a vicinal arrangement of redox active residues (Cys-Sec or Cys-Cys), it uses a spacer of four residues to separate the two redox active Cys residues for a sequence of G534C1GGGKC2G541.
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