Your English writing platform
Discover LudwigExact(1)
We then explored SAR around substituted thiophenes: compounds 7 k– p. Clear improvements in potency were observed with benzothiophene (Table 2, compound 7 p, KD=1.6 μ m) and halogenated thiophenes, most notably thiophene 7 m, which has a KD value of 1.3 μ m.
Similar(59)
So go on Jeremy, next time around substitute that supercomputer for a scale model of the Grand Canyon and a train set.
Any large conformational changes corresponding to the reduction of B factors around the substituted sites were not observed.
For example, if you consider a para-substituted phenyl ring where two conformations differ by a rotation of 180° around the substituted carbons, it is clear that the calculated RMSD between the conformations should be 0.
By analyzing the local structural environment around the substituted amino acids, we were able to develop physiochemical hypotheses as to the effect of the substitution on enzyme activity and co-factor binding.
The sounds of the words are fragmented in every way imaginable: syllables get shifted around, vowels are substituted for one another, parts of words are combined into new words, some as nonsensical as anything in Gertrude Stein.
The TMACC interpretation identified the methyl of methoxybenzyl groups substituted around the benzoic acid moiety of inhibitor molecules as positive for activity.
The short-range order around Ti atoms substituted for Al in hexagonal lattice undergoes strong distortions when the film is submitted to indentation test.
Between 1979 and 2011, Brazil substituted around 22 million pure gasoline-powered vehicles with 5.7 million neat ethanol vehicles, 14.8 million flex-fuel vehicles and almost 1.5 million flex motorcycles.
Interlocking of two 6,6′-BODIPY substituted bipyridines around a single copper(I) center is observed by proton NMR and cyclic voltammetry.
Based on DFT calculations, the most significant effect on orientation of (un)substituted ligands around cobalt, i.e. cis trans isomerism, comes from crystal packing.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com