Sentence examples for aromatic scaffold from inspiring English sources

These compounds are derived from a planar, aromatic scaffold and functionalized with four points of diversity.

Designed compounds were rapidly synthesized from a key aromatic scaffold via microwave-assisted Suzuki-Miyaura coupling/CH direct arylation sequence.

The sialyl molecule was designed based on the NeuAc WGA complex in the Protein Data Bank and featured polyethylene glycol linkers connecting to an aromatic scaffold.

Two new families of chiral arenesulfonic acids were synthesised in a short, robust and scalable synthetic sequence involving a key cross-coupling step of an aromatic scaffold with a suitable chiral auxiliary.

Another aromatic scaffold, phenylthiazolyl-hydrazide was identified from a drug screen as a tau aggregation inhibitor.

These novel molecules mimic GAG structure through appropriate placement of one or more sulfate group(s) on an aromatic scaffold.

In the first part are brought together and evaluated most convenient synthetic methods that can be employed for the preparation of TPM and TPSi aromatic scaffolds and of their corresponding tetrabromo derivatives (TPM-Br4 and TPSi-Br4).

Dataset Occurrence of scaffolds (% relative to dataset size) No. of singletons (% relative to number of scaffolds) Aromatic scaffolds (% relative to number of scaffolds)   No.

In 2006, Ertl and coworkers investigated the simple aromatic ring systems present in a set of 149,437 bioactive compounds and only 780 unique simple aromatic scaffolds [11].

Processive crown ether migration on an oligoglycine chain and migration of metal atoms on aromatic scaffolds have also been explored.

Here we report the use of bis-amido aromatic scaffolds conjugated to an epoxide warhead as inhibitors of the NS2 autoprotease.