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Such series of experiments are important to separate contributions arising from the sample holder (and connection cables) and electrodes from the sample itself.
The interferometer contains adjustable path length-matching optics and compensating glass coverslips in the reference arm to offset differences in bulk dispersion arising from the sample and other interferometer optical elements.
The results highlight the importance that for any expression profiling study using LCM cell-sampling, steps are taken to evaluate all possible bias arising from the sample processing methods.
The model predicts the percentage of differentially expressed elements by calculating the proportion of variation arising from the sample treatment, as opposed to the variation introduced by experimental effects [ 3].
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28 The data set was adjusted and weighted for clustering arising from the sampling design, taking into account camp and household population variations.
Standardized weights were assigned to the data to account for differences in selection probabilities between different clusters of MSM arising from the sampling design [ 7, 11]; clusters were also taken into account, using the Complex Samples module in SPSS.
For example, among those who have been involved in the use of MTAs as a receiver of samples, only 33.3% agree that local scientists should be authors on all papers arising from the samples, whereas this agreement is at 49.3% among those who have been involved in the transfer of samples.
Variability in test results was studied, which may arise from the sample drawing site.
Verbeek and Nijman (1992) propose the latter as a simple means of both testing, and controlling, for the selectivity bias that might arise from the sample attrition that occurs during the course of a panel.
Limitations of this study arise from the sample size.
10, 19, 25, 29, 32, 33 Another complication arises from the sample tapering typically observed during FIB fabrication when using annular milling.
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