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Hence, by the present argument, patients with MAPT mutations should show low (normal) plasma TDP-43 levels and those with PGRN mutations should show high er) plasma TDP-43 levels.
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To support the argument that patients with stage IIB disease fare worse than patients with stage IIIA, a Dutch study that examined 2,282 patients with all stages of colorectal cancer [ 9] demonstrated that patients with stage IIB tumors had a higher risk of developing locoregional recurrence when compared to patients with stage IIIA.
Contrary to the argument that "patients won't do this," we find that patients rejoice once they understand their disease and how they may halt it.
Much has been made of the argument that patients are largely to blame for skyrocketing health care costs because of their unhealthy lifestyles and overuse of medical services.
This seems to be in line with the argument that patients will risk negative impacts on quality of life for survival gain.
These data cast doubt on the argument that patients benefit maximally from barbiturate protocols that include EBS as a therapeutic target, especially given the frequent adverse effects of hypotension and immune dysfunction.
Hurd and Clarke make the compelling argument that patients' engagement in self-management is in part driven by a desire to regain control over their bodies [ 32], which appeals to the notion that chronic illness, and indeed multimorbidity, present opportunities for patients to invoke a moral discourse and reinstate agency and self-determination through self-management [ 33].
In all cases, the IRBs accepted the argument that patients and their families are often vulnerable in the early post-trauma period, and require some time period to adjust to the severity of the patient's injury, and provide informed consent.
In addition to the changes on the demand side (which are not germane to the economic argument, as patients will continue to have a mixture of agents acting on their behalf and some degree of individual choice), there has been a serious attempt to introduce full economic regulation.
This study supports the argument that patient experience, clinical effectiveness and patient safety are linked and should be looked at as a group.
It is however striking that no discussion was documented about the role of equality, neither as a possible negative side-effect of patient choice nor as part of the argument for patient choice.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com