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For trials involving children living in an endemic area, trials were also grouped by prevalence and intensity (high/moderate/low).
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There is therefore an urgent need to evaluate the effectiveness of ITN's in a large-area trials under realistic programmatic conditions [ 32] where the distribution of nets is heterogeneous but not experimentally controlled and both treated and untreated nets co-exist under representative conditions of availability, use and maintenance.
It is not clear exactly what sparked the fight in the Denver area last Sunday, but one reason given -- similar to the explanation offered at the Boston-area trial -- was the fierceness of the play on the ice.
In principle, such immigration could be limited by culling within geographical features which present barriers to badger movement (as in the areas selected for culling in Ireland's Four Areas Trial [18]).
This study, conducted in the Republic of Ireland and known as the Four Areas Trial, found reductions in cattle TB incidence ranging from 51% to 68% over a five-year culling period [18].
Feasibility studies are an important component of preparations for efficacy field trials of vaccine candidates, but represent a neglected area in clinical trial literature.
Such experiments are widely used in areas such as clinical trials, experimental psychology and agricultural field trials.
For an adequate representation of the contrast between the area where trials are needed and the area where trials are conducted, we constructed an area cartogram according to the method developed by Gastner and colleagues [17].
In AREA DOTS trials, the summed area of the dots was constant (A = 15 cm).
In AREA DOT trials, the summed area of the dots was constant (A = 10 cm), with the individual dots ranging in size (from radius r = 1.78 cm to r = 0.59 cm).
The debate over whether to repopulate the area, if trial cleanups prove effective, has become a proxy for a larger battle over the future of Japan.
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