Sentence examples for area of deletion from inspiring English sources

In order to pinpoint more precisely the area of deletion, nested PCR with pairs of specific primers was designed according to the earlier PAMP results.

Group 1 is characterized by large area of deletion in chromosome 8.

Allelic losses at the central and distal areas were associated significantly with aggressive behaviour of the disease (16q24.1 q24.2, P< 0.01, and 16q24.3 qter, P< 0.05), and the central area of deletion was further significantly associated with poorly differentiated tumour cells (P< 0.05) and with recurrent (P< 0.01) growth of the tumour.

Overlapping areas of deletion defined the smallest regions of overlap (SRO).

Moreover, for the other two areas of deletion, the losses of DNA were confirmed to span the same areas in the MIN-Os and the tumors.

In ATC, large areas of deletions were observed, always including loss at 13q21.

RESULTS: Analysis of genome-wide, SCNA revealed that the DIAPH3 locus was a consensus area of chromosomal deletion common to several carcinomas.

Nevertheless, no shared region of deletion has been identified among the autistic patients with 18q deletion.

The frequency of alteration for each BAC was then individually determined for each lung cancer cell type as described previously and plotted in SeeGH Frequency Plot to visualise areas of recurrent deletion and amplification (Coe et al, 2006).

In addition, Birger and colleagues (2006) identified significantly down-regulated genes located in the area of the common deletion site, of which at least one, HMGN1, has been associated with tumor growth in mice and primary mouse embryonic fibroblast cell lines [ 32].

We identified a consensus area of significant recurrent deletion on chromosome 13 encompassing the DIAPH3 locus and showed that DIAPH3 genomic loss and/or decreased DIAPH3 expression occurs in organ-confined tumours, but occurs at higher frequency in advanced disease, circulating prostate tumour cells, and metastatic lesions.