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Compared with wild type cells, SMCs lacking LRP1 showed markedly increased migratory activity, both in a Boyden chamber transmigration assay (Figure 5A, C) and in the commonly used scratch assay, in which the migration of the cells into a denuded area of a tissue culture dish is quantified (Figure 5B, D).
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This study aims to investigate the effects of orthodontic expansion on graft area of a tissue-engineered bone (TEB) BMSCs/β-TCP, and to find an alternative strategy for the therapy of alveolar cleft.
2) Since oxygen-depleted areas of a tissue coincide with nutrient-depleted and energy-depleted areas [50], we assume that oxygen serves as the single limiting substrate field.
Only small amounts of RNA are required to examine specific areas of a tissue obtained by laser microdissection.
To calculate the apoptotic index, five images of different areas of a tissue section covering most of the section were taken from three independent tissues for each group.
Oxygen levels vary considerably in different tissues – and even in different areas of a single tissue – and depend on a complex interaction of physiological variables, particularly the balance between the vascular supply and the metabolic demands of the tissue.
Tissue cylinders with a diameter of 0.6 mm were punched from morphologically representative cancer areas of a donor tissue block and brought into a recipient paraffin block (30 × 25 mm), using a semiautomated tissue arrayer.
With BMP, starting from a uniform distribution of progenitor cells localized in a small local area of the tissue, a single crypt is formed at the steady state.
In comparison, reactive thickened fibrous capsule in a node containing an area of necrotic tissue had a slightly lower attenuation coefficient μ t ≈12mm−1.
Briefly, tissue cylinders with a diameter of 0.6 mm were punched from representative tumour areas of a 'donor' tissue block using a semiautomatic robotic precision instrument.
In univariable analysis, younger age, lower BMI, and pre-menopausal status, a greater percent density, a greater area of dense tissue, and a smaller area of non-dense tissue, were all significantly and positively associated with breast cancer detected within 12 months of a negative screening examination.
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