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The phrase "are widely different" is correct and usable in written English.
It can be used to describe two or more things that have significant differences or variations between them.
Example: "The two cultures are widely different in their traditions and values."
Alternatives: "are significantly different" or "are markedly different".
Exact(30)
China comprises a vast territory: its natural conditions are complicated, economic development levels are widely different, and regional differences in rural household energy consumption are apparent.
Home schooling is legal in all 50 states, although there are widely different regulations.
Most individual E.U. member states do collect data, but collection is often spotty and definitions of rape and violence are widely different in different justice systems.
When a magnetic field is applied, these levels become separated sharply; i.e., the corresponding energies are widely different, with the lowest levels occupied by dipoles most closely aligned with the applied field.
As resources and constraints are widely different between infrastructure development contexts, the framework does not provide explicit methodological choices but presents current limits of knowledge and know-how.
The acoustic needs of theatre and music are widely different, and acoustic shields (suspended or freestanding panels used to alter the acoustic properties of a space) are at best corrective devices.
Similar(30)
The answers have been widely different.
It was diverse, it was widely different across geographic areas, it had lots of different doctrines.
It is obvious that our social spheres have been widely different".
The surface adhesive properties were widely different compared to wild-type avidin.
Writers were frequently featured as central characters in Canadian novels published in 2014, though their story lines were widely different.
More suggestions(18)
are greatly different
are generally different
are widely distinct
are commonly different
are widely various
are widely divergent
are widely disparate
are widely differing
comprise widely different
are widely varying
are vastly different
is broadly different
are broadly different
are very different
are significantly different
are strongly different
are quite different
are very diverse
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com