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Certain metal nitrides are unstable, and most react with water to form ammonia and the oxide or hydroxide of the metal; but the nitrides of boron, vanadium, silicon, titanium, and tantalum are very refractory, resistant to chemical attack, and hard and thus are useful as abrasives and in making crucibles.
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In fact, SUNCT can be very refractory to therapy.
Accordingly, because the patient was very refractory, and also because of some peculiar clinical findings, we speculate on the pathophysiology of the disease.
Since no intermediates other than free radicals generated following energy deposition and their interaction with the DNA molecule are involved [32], [33], [34], it appears theoretically unlikely that heterochromatin would be very refractory to DSB generation by IR.
Most interestingly, although the separation from the mainland populations may be relatively recent, the now established population seems to be very refractory to further genetic immigration.
The resulting nitride (TiN), carbide (TiC), and borides (TiB and TiB2) are interstitial compounds that are very stable, hard, and refractory.
Naturally occurring, malaria resistant strains are termed as refractory mosquitoes and these are very rare in the field.
These tumors are very rare and no second-line therapy for patients with refractory disease exists.
These results are very promising, as one-third of the study population were either receiving second-line treatment and/or were anthracycline-resistant/refractory.
This accurately represents patients with relapsed/refractory or transformed FL undergoing allogeneic HSCT and whose expected outcomes are very poor [ 30].
The glasses can accordingly be classified as being both very refractory and very fragile.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com