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These findings are useful for refining existing treatments, for developing novel diagnosis and treatment protocols for migraines, and for determining preventative strategies for the chronification of migraines [23 27].
We believe the interaction effects uncovered by CWAS are useful for refining structural alerts and enhancing model interpretation, enabling more effective design of safe chemical substances and leading to the improved regulatory chemical risk assessment.
A more important aspect to consider is whether or not these tests provide estimates of bioaccessibility that are useful for refining bioavailability and Pb exposure assessments.
In a recent study, Cuzick et al evaluated a panel of 15 SNIPs and found that they are useful for refining risk estimates in women at high risk of developing breast cancer.
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This approach has been widely used for CGH data and is useful for refining our list of genes potentially affected (Tonon et al, 2005; Lockwood et al, 2008).
Presently we lack detailed mechanistic information about this potential extra source of dNTPs, which would be useful for refining the model.
This information would be useful for refining the predictive model.
The combination of available tools, including minimal residual disease assessment, with these easily measured predictive features could be useful for refining the indications for bone marrow transplantation [ 19- 22].
This information has been useful for refining the geographical origin (Perrier et al., 2009, 2011), but is not detailed enough to assist with breeding strategy.
Data from further studies of parasite physiology will be useful for refining the imputation model, to incorporate additional variation and more accurately impute lowly expressed genes.
Both false positive and false negative results can be useful for refining model content, but it is the false negative cases that can help fill gaps.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com