For common diseases, the observed small effect sizes of individual gene variants limit diagnostic potential, and given that most variants identified have an unclear function, how to target the corresponding gene for therapeutic intervention is typically unclear.
The sagittal view is especially helpful in defining rostral portions of the hippocampus, which is typically unclear in coronal views.
It is typically unclear to what extent climate-induced species distribution shifts simply reflect the sum of different populations moving to new areas as they each track the changing location of their environmental 'niche'niche
Ovarian germ cell tumors are not associated with an altered endocrine environment; however, the mechanisms of toxicity for compounds that induce ovarian tumors in rodents are typically unknown or unclear.
The clinical findings for R. felis infection are often unclear and are typically misdiagnosed as other febrile illnesses (12, 31 ).
Treatment effects, even for therapies demonstrating "benefit", are typically small and it remains unclear if treatment benefits persist beyond 6 months [ 13].
160– 162 Because rheumatoid arthritis patients are usually on concomitant systemic immunosuppressants while psoriasis patients are typically treated with monotherapy, it is unclear if safety data from rheumatoid arthritis studies can be generalized to psoriasis.
The role of other genes, such as Gng2, in SSeCKS regulation remain unclear although they are typically involved in specialized neuronal signaling responses [ 26]; upregulation might suggest that SSeCKS induces signaling pathways more associated with differentiated, especially neuronal, cells.
It was unclear whether the rockets, which are typically not very accurate, struck or came close to their intended targets.
Control screening examinations as a follow-up are typically done for breast and cervical cancer screening to check unclear test results.
But evidence for that is unclear, and a statistical model by Yair Ghitza and Andrew Gelman found that preferences in politics are typically set at an early age, with lasting influence.
