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The phrase "are two major problems" is correct and usable in written English.
It can be used when identifying or discussing significant issues or challenges in a particular context.
Example: "In our analysis of the current situation, we found that there are two major problems affecting our progress."
Alternatives: "exist two significant issues" or "present two key challenges".
Exact(50)
There are two major problems.
At very best there are two major problems with ideology.
There are two major problems with Lehr's argument.
There are two major problems with this story.
It all creates a dreamy cinematic excitement, but there are two major problems.
However, when it comes to accessing nondrug treatments for pain, there are two major problems.
Similar(10)
There are four major problems with this deal.
But there are four major problems with growth hormone as an elixir of life.
There are three major problems with software projects: over budget, behind schedule, and poor quality.
I've worked on clean-energy policy for twenty-five yeand, and I have observed that there are three major problems with a carbon tax: First, it relies too much on the assumption that any small tax will somehow alter markets.
But there are three major problems with these new regulations.
More suggestions(15)
are two major projects
are two important problems
are two serious problems
are two large problems
are two major shortcomings
are two principal problems
are two major constraints
are two major errors
are two enormous problems
address two major problems
present two major problems
are two major components
are two apparent problems
are two major disadvantages
are two major critics
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com