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Evidently, only those parameters are suitable for validation, which are not implicitly defined in a model.
Standardization of sample preparation protocols should increase reproducibility of these studies, and will make it easier to select candidate genes and proteins that are suitable for validation as biomarkers for either fibrosis staging, or as predictive biomarkers for disease outcome and/or treatment response.
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The density of information yielded by electrical tomography is suitable for validation of Computational fluid dynamics.
Although the two non-neuronal tissues we have tested here have provided limited utility in identifying SZ-associated gene expression abnormalities, it is plausible that very large case-control samples (to reduce individual variation/SZ heterogeneity) of LCLs or fibroblasts may be suitable for validation (e.g. by qRT-PCR) of a small number of genes identified via other means.
This new model A20 myel-KO might be suitable for validation of therapies targeting NLRP3-inflammasome or IL-1 signaling.
The algorithm outperforms several methods currently used, providing considerably better accuracy and it is suitable for validation of known splicing events as well as for exploration and discovery of novel non-annotated transcripts in human samples.
Progress so far has been hampered by a lack of spatially resolved data including measurements of concentration, which are suitable for CFD model validation.
The reduced frequency MSEs include only modelled data and so are suitable for the experimental validation of the simulation.
The methods found to be suitable for validation of the cleanliness were visual observation of a fluorescent indicator using UV-light, a contact agar method and culturing based on swabbing and swiping with non-woven cloths.
Finally, guidelines for the design of WDR gauges and for the selection of WDR measurement data that are suitable for model development and model validation are given.
Cross-validation demonstrated that both MFI and the affected area are suitable for classification of RA as individual parameters.
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