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The phrase "are substitution" is not correct in English and does not convey a clear meaning.
It may be intended to refer to a type of substitution, but it lacks proper context and grammatical structure.
Example: "The options we have for the project are substitution methods that can enhance our results."
Alternatives: "are replacements" or "are alternatives".
Dictionary
are substitution
noun
The act of substituting or the state of being substituted
Exact(16)
Agricultural landscapes structured by trees are substitution habitats for some species that inhabited mature trees of primeval forest.
The samples of Pd Co alloys prepared here are substitution solid solutions where some atoms of Pd are replaced by Co atoms.
The most important steps are substitution of complex constraints with sets of simpler ones and insertion of redundant constraints by solving triangles and determining sums and differences of adjacent angles.
What is left in the underlying language, with identity excised, are substitution rules (Tractatus 6.23).
The new set is now wherein are substitution pixels for noisy pixels by linear prediction from noise-free pixels.
On the other hand, (r → r) → r → r and ((s → s) → s → s) → (s → s) → s → s are substitution instances of p → p and of q → q.
Similar(44)
Formulas so formed, however, are valid when and only when they are substitution-instances of valid wffs of PC and hence in a sense do not transcend PC.
In their 1989, Crimmins and Perry respond to Richard's challenge by accepting that there are substitution-failures even outside the scope of attitude verbs.
With the fact that there is substitution we can have no legitimate quarrel.
The next matches were substitution isomers.
Our primary outcome is substitution of care.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com