The phrase "are substantially responsible" is correct and usable in written English.
It can be used to indicate a significant level of accountability or causation in a particular situation or outcome.
Example: "The recent changes in policy are substantially responsible for the increase in employee satisfaction."
Alternatives: "play a major role" or "are largely accountable".
"He was substantially responsible for creating the situation," one of the officials said in a telephone interview.
And 75 percent of respondents said that human behavior was substantially responsible for any warming that has occurred.
The new rules allow the F.D.I.C. to reclaim compensation from senior executives if they were "substantially responsible" for the bank's failure.
And the business judgment rule will no longer shield decisions from subsequent scrutiny by the courts assessing whether an executive was substantially responsible for a bank's demise because now executives must show they acted with due care.
Late Friday, the Federal Housing Finance Agency, the new overseer of Mac 'n' Mae, said it might limit the payment of legal fees and exit packages if it had reason to believe the recipients committed fraud, breach of fiduciary duty, were substantially responsible for the insolvency of either entity or violated regulations.
An important facet of the rule creates a presumption that the chairman of a company's board, the chief executive, the president and the chief financial officer, or someone removed from one of those positions by the F.D.I.C., is substantially responsible for the bank's demise if the person had authority over "strategic, policymaking or companywide operational decisions".
Every year around this time it seems fitting to give thanks to horror-movie fans, whose willingness to support their genre of choice by actually laying cash on the line is substantially responsible for keeping a lot of studio library divisions and independent video companies in operation.
Restrictive bend in antibiotic prophylaxis guidelines could be substantially responsible for these trends.
HH was substantially responsible for the machine development.
These two pathways might be substantially responsible for the incidence and progression of DLBCL.
