The phrase "are substantially out" is correct and usable in written English.
It can be used to indicate that something is significantly incorrect or not in alignment with expectations or standards.
Example: "The figures in the report are substantially out, leading to a miscalculation of the budget."
Alternatives: "are significantly off" or "are greatly inaccurate."
Alternatively, the new link will have a label that is substantially out-of-alignment with the current hypothesis (after having learnt a number of link-labels).
Moreover, he said, if Medicare officials find that an insurer is "substantially out of compliance" with federal requirements, they can terminate its contract this year.
If your sleep-wake schedule is substantially out of sync with your work-play schedule, you probably suffer from some or all of these symptoms.
"A building of this scale, rising to 348 feet, would be substantially out of character with, and overwhelm, the neighborhood," Joseph B. Rose, the planning chairman, told the appeals board last December.
He was also, for a brief period, the editor of Jazz Magazine International, but was substantially out of pocket, as were the writers, myself included, when the magazine folded in 1995.
But Mr. Wolovick suggested that by the time such a count was completed it would be substantially out of date, given that many schools are replacing computers and software using tens of millions of dollars provided by the Giuliani administration beginning last year.
Of California's 112 community colleges, one, College of the Sequoias in the Central Valley town of Visalia, is operating under the most serious penalty — "show cause" — meaning the college is substantially out of compliance with requirements and must correct deficiencies to remain accredited.
Bobb faulted Tabatabainejad for failing to identify himself in the first place and the police for a response that was "substantially out of proportion with the provocation". Bobb points out, for example, that Duren used the Taser in the "drive/stun" mode in which the device is pressed against a person's body as opposed to shooting a wire-bearing dart from a distance as police typically do.
In short, when violence breaks out, women are substantially less likely to have started or to carry out the conflict and substantially more likely to suffer at the hands of those who did.
The distributions of relative ranks for the three different methods are shown in Figure 3. Across all homology groups, the relative ranks computed by SOPH for the left-out interactions are substantially lower than we would expect by chance, with a mean relative rank of 0.23, and median rank of 0.16, indicating that the left-out edge is nearly always in the top 25% of the possible edges.
