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The reconstruction model suggests that observers are substantially less sensitive to variations in the depth of a pole than they are to variations in lateral position (Fig. 3).
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As first demonstrated for [177Lu]pentixather, the pentixather scaffold is substantially less sensitive towards structural modifications than pentixafor (Schottelius et al. 2015; Herrmann et al. 2016).
Tolerance studies show that the rectangular segment PMQ design is substantially less sensitive to the easy axis orientation errors and hence will be a better choice for DTLs.
Two-electrode voltage clamp studies of amantadine block also showed that both Kcv* and the T63S mutant were substantially less sensitive to the blocker than the wild-type channel (Figure 5).
This assay is substantially less sensitive than reverse transcription PCR.
The nonmalignant cells in our panel were substantially less sensitive.
Normal prostate epithelial cells were substantially less sensitive to AGN194310 than carcinoma cells.
However, p38 is substantially less sensitive to PEITC mediated inhibition than SAPK.
However, like many mutations that cause DEND syndrome, hetT293N channels were substantially less sensitive to tolbutamide (36% block).
Conventional cell culture in MDCK cells, rapid culture, and quick test assays were substantially less sensitive (55%, 72%, and 39%, respectively).
Another interesting finding of the present work is that nonmalignant cells (fibroblasts and PBMNC) were substantially less sensitive to RITA than tumor cells, making RITA an interesting tumor-selective drug.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com