The phrase "are substantially easier" is correct and usable in written English.
You can use it when comparing the difficulty of two or more tasks, indicating that one is significantly less difficult than the other.
Example: "The new software updates are substantially easier to navigate than the previous version."
Alternatives: "are significantly simpler" or "are much easier".
Yet the less versatile bacterial regulators of translational initiation are substantially easier to engineer.
Moreover, in our experiments the small contact regions observed cause only small cellular deformations, and our target Jurkat T cells are substantially easier to deform than some other cell types, such as neutrophils and HL60 cells [28].
However, some aspects of microbial ecology are substantially easier than in large-organism ecology.
These planar trees are substantially easier to analyze: for example, there is a nice closed form generating function for the numbers of such trees (the Catalan numbers).
It is "dramatically cheaper to start a company now," he wrote, so it is substantially easier to build a business, sometimes without needing venture capital.
In comparison to conventional Chemical Looping Combustion (CLC) carried out in fluidized beds, the GSC concept will be substantially easier to design and scale up, especially under pressurized conditions.
It will have to happen one day but United's experiences with David Moyes reiterate that the job will be substantially easier for the manager two places down the line.
Moreover, the labor force will drop faster than the population, because of shifting composition, so it is substantially easier to make the case that per capita productive capacity might actually be lower at some future date than it is today.
The good news is the Rangers' schedule, which appears to be substantially easier than that of two of the teams directly above them, the No. 9 Atlanta Thrashers and the No. 8 Boston Bruins.
On the whole, it was substantially easier to defend a fortified position than to attack one, and even a small force could achieve a disproportionate military advantage by occupying a defensible place.
