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CNV among T. cruzi strains are substantial in number, widespread throughout the T. cruzi genome, range in size from a few hundred base pairs to whole chromosomes (based upon the assembled CL-Brener genome), and are discordant with traditional DTU assignments for the strains tested.
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We here report a series that is substantial in numbers and in follow-up.
In fact, the predictive power of these three variables was substantial in modeling the number of weeks to DFU closure (c-statistic = 0.75).
There was substantial variation in number and pattern of indel, however, with more and larger indels observed in BRCA1 and BRCA2 mutant cancers.
In addition, there are substantial differences in the number of patients studied (and duration of treatment) with each drug (Table 3) [ 63, 81, 116– 116].
The most surprising finding is that, though not as common as in archaea, there are substantial numbers of leaderless genes in bacteria.
There are substantial variations in the annual number of phone calls per inhabitant to municipal out-of-hours services [ 7].
We have shown that there is substantial copy number variation in coding sequences in the C. elegans genome.
In recent years there have been substantial increases in the number of people dying in the UK where illicit drugs are reported to be involved in their death.
After 1982 and the approval of Medicare reimbursement for ASCs, there has been substantial growth in the number of ASCs in the United States.
There has been substantial progress in the number of pilgrims during the last 92 years, and the number of foreign pilgrims has increased phenomenally by approximately 2,824 percent, up from just 58,584 in 1920 to 1,712,962 in 2012.
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