Sentence examples for are substantial challenges from inspiring English sources

There are substantial challenges, economic and social, and forceful demands for more freedom, especially among women and young people.

Hydrogen is considered a sort of holy grail of fuel, but there are substantial challenges to its development.

There are substantial challenges in designing such a vehicle, which appears to have been one of the factors that drew Reitz towards the project.

What all these companies share, industry analysts say, are substantial challenges in making rich, colorful Web content easy to read and navigate on mobile devices, which are hampered by small screens, slow speeds for gaining access to data and limited battery life.

However, there are substantial challenges with the pharmacokinetics of rapamycin due to its lipophilic chemistry [32].

There are substantial challenges ahead, from data protection alignment between countries and companies, to London potentially losing the right to clear euro-denominated securities – a disaster for money transfer firms.

Despite impressive growth in the first year of operations, Mr. Fils-Aime said there were substantial challenges to operating a wireless carrier in Haiti.

He also argued there were "substantial challenges" with enforcing a ban on smoking in cars particularly vehicles "travelling at speed", questioning whether people would comply with the law if they knew there was little chance of it being enforced.

However, across all six service areas there were substantial challenges in relation to information, which can be grouped into two main types.

Massive amounts of high-dimensional data have provided us new opportunities to advance biological and biomedical research; however, there have been substantial challenges [ 2- 4] in the storage, analysis, integration and reduction of those cross-platform, multi-dimensional, heterogeneous data in order to identify true biological signals, biomarkers and disease susceptibility genes.

Conversely, although we are conceptually clear as to how different components of the overall study design relate, we believe that there will be substantial challenges in synthesizing data collected through different WPs and understanding the broader chain of connections between transition preparedness, program institutionalization, and sustainability outcomes.