Also, clusters 6 and 7 contain genes that are expressed at the earliest floral stages and are subsequently down-regulated.
The alignment results were subsequently down-lifted to hg16 (liftOver, UCSC) to compare to other tracks generated from the tiling microarray technology.
A second group includes the genes whose expression peaks at day 1 after ES cells have been plated in RHB-A, being subsequently down-regulated in NPs and neural rosettes.
Oct4, a key regulator of the pluripotent phenotype, is first expressed in the inner cell mass of the blastocyst, but is subsequently down-regulated and eventually only expressed in germ cells [48].
In contrast, resistant mice, who did eradicate the spirochetes without showing any clinical signs of infection, showed initially strong Th1-responses, that were subsequently down-regulated by an ensuing Th2-response.
It can be speculated that a transient anti-inflammatory response is induced in very young goats shortly after MAP infection which is subsequently down-regulated by a strong IFN-γ response indicative of pro-inflammatory mechanisms.
In the developing heart, Twist1 expression is robust in the mesenchymal cells of the ECC and is subsequently down-regulated during remodeling and differentiation of the valve leaflets [ 9, 10].
The data were subsequently down-sampled to 250 Hz using SPM8 (http://www.fil.ion.ucl.ac.uk/spm/), and epoched from −400 to 800 ms relative to the onset of the memory array.
Here, a variety of catalytic sites degrade the substrate into short peptides that are subsequently broken down to amino acids by peptidases and recycled by the cell.
Four of the Blenheims were subsequently shot down by CAP fighters and one was shot down by aircraft from the carriers' returning air strike.
The suggestion was subsequently watered down.
