HLA-E is highly stringent regarding its peptide ligands, with leader sequences from certain HLA-A, -B, -C and -G alleles being its natural ligands.
However, Takuno and Gaut (2012) were more stringent regarding the estimation of Ka/Ks by requesting the aligned sequences to include at least 100 synonymous sites, which was not requested for the Ka/Ks estimation in the dataset used in this study (Lloyd et al. 2015).
Because although the laws are stringent for long-term marriages regarding spousal support and dividing assets 50/50, teams of extremely savvy lawyers and accountants have devised myriad strategies for the primary breadwinners (in these cases all of the primary breadwinners happened to be the husbands) to "protect" and "retain" (i.e., hide) incomes and assets.
Our laboratory criteria to diagnose HME in this study are patterned after those of the Council of State and Territorial Epidemiologists (CSTE), although our criteria are even more stringent regarding PCR interpretation (24 ).
Two screening tests are available (OECD 311, ISO 11734), which are characterized by a low microbial density (a small inoculum) and the fact that the test substance is the only carbon source, i.e. the test conditions are stringent but not necessary realistic with regard to the fate of chemicals like surfactants.
Analysis of the test run under submerged conditions reveals that the tests ASTM D 5210, ISO 11734, ISO 14853, OECD 311 and the ECETOC test are characterized by a low microbial density (a small inoculum) and the fact that the test substance is the only carbon source, i.e. the test conditions are stringent, but not necessary realistic with regard to the fate of chemicals like surfactants.
These are stringent, but not impossible, qualifications.
These are stringent conditions.
The award criteria are stringent.
The laws governing DUI violations are stringent.
Rationing must be stringent.
