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These miRNAs are speculated to regulate the expression of type I and type III collagens but also the laminin γ chain LAMC1.
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Thus pkn2 is speculated to regulate the activity of penicillin binding proteins.
A potential regulatory element at the 5'end of the IgH locus was speculated to regulate processes such as IgH allelic exclusion, VH germline transcription, differential accessibility or usage of distal versus proximal VH gene families.
The ability of BLU to regulate transcription is speculated to influence the level of proliferation regulators, and engagement of signaling pathways involving JNK and cyclin D1 may mechanistically elucidate the tumor suppressive role played by BLU.
Observations suggest these epimutations have a genomic feature of CpG deserts that are speculated to have significant roles in regulating genome activity [ 22].
In contrast, the rapid and transient induction of miR-9, miR-146a and miR-155 has been speculated to negatively regulate the acute responses following activation of innate immune through down-regulation of proteins involved in the receptor-induced signalling pathways.
However, considering that avian influenza causes an excessive immune response, it could be speculated that appropriately regulated immunity does not hamper the body's normal resistance to AIV.
Because SPS1 is localized to both plasma and nuclear membranes [ 38], it can be speculated that SPS1 regulates signal transduction by transducing signals on the plasma membrane or by transporting messengers or transcription factors through the nuclear membrane.
It can be speculated that Rab2 regulates the trafficking of lipid containing vesicles during the chylomicron formation in the intestine.
Considering all these observations, it is speculated that curcumin regulates the expression of p53, which in turn modulates the expression of several miRNAs.
It has been speculated that STAT3 36 regulates expression of MYC (Fig. 1), which may have potentiated apoptosis in the present study.
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