7, 8 The promoter of the ATPRB1 gene has been shown to have organ-specific expression patterns and is specifically responsive to the treatment of Et and Me-JA while treatment of SA represses its expression.
The gene encoding CA9 conforms to a pattern first described among genes encoding glycolytic enzymes (Hu et al, 2003), and is specifically responsive to HIF-1 α, showing no response to HIF-2 α in any cell type, whether non-RCC or RCC (Grabmaier et al, 2004; Raval et al, 2005).
This reporter, which consists of 12 repeats of Notch-responsive elements driving EGFP expression (Moro et al., 2013), is specifically responsive to Notch signaling, as manifested by its dose-dependent downregulation in response to DAPT treatment (Fig. S4).
Of these, 14 spots were found to be differentially expressed in response to 300 µM H2O2, while the other 14 spots showed significant changes under 600 µM H2O2 (Table S1), indicating that these spots were specifically responsive to a treatment concentration.
Therefore, we could not determine whether miRnov_6 or miRnov_9 was specifically responsive to Pi.
Considering this, EPCs must be specifically responsive to signals present at injury and remodeling ECs as opposed to signals present in normal and quiescent ECs.
This pattern suggests that the regulation of a substantial portion of RR-WCR's transcriptome is specifically responsive to brief soybean herbivory.
Moreover, these proteins were absent from the culture supernatant of the respective transformants when 10 μM CuSO4 was included, suggesting the expression was specifically responsive to the copper.
Second, the luciferase intensity of PRTG-UTR was specifically responsive to miR-9 over-expression suggesting that miR-9 may regulate PRTG protein expression by inducing translational suppression.
Using this approach, we obtained 13 and 9 genes that were specifically responsive to a predation threat by dragonfly and larval salamanders, respectively.
A comparative microarray study investigating the effects of IGF-1 and insulin (employing ~2222 probe sets) has shown that 30 genes were specifically responsive to IGF-1 and 9 genes to insulin [ 11].
