(C ) Heat map of ChIP-seq enrichments across all genes that are significantly bound by Pol II during MBT.
To determine how many of the compensated genes are significantly bound by the MSL-complex we used available MOF binding data from male salivary glands [ 28].
62 out of 70 robust TFs, and 12 out of 13 fragile TFs have at least one cooperative TF (Additional file 1), that is, the TF cohort genes are significantly bound by at least one other TF (Bonferroni corrected P < 0.01, Mann-Whitney U-test).
Nevertheless, the result shows that high a (alpha^{ k)}) is significantly bound to higher employment, and lower unemployment rates, and that the overall shape of the activity timeline can give us more information than just using one feature of a whole day.
"Any materials including residual metals still on towels after laundering would have to be significantly bound to the fibers, making any transfer from towel to hands or mouth virtually impossible".
From the docking result of Z-dock, we proved the AP1 is significantly bound to TFIIB.
ACTA2, RNASE7, and AXL were identified to be significantly bound by p73 in untreated HCT-116- 3 HCT-116- 3 HCT-116- 3 0.005.
In HU-treated HCT116-3 6) cells, EPA2R, TRIM22, ACTA2, and RNASE7 were identified to be significantly bound by p73, with FDRMAP < 0.005 (see Additional file 8).
We identified 3465 genes that were significantly bound by Rfx2 and, importantly, this set of genes overlapped significantly with the set of genes differentially expressed in Rfx2 morphants (p≤10−6, hypergeometric test).
We considered a feature (e.g., exon, intron) to be significantly bound with a given protein if greater than 10% of its length was overlapped by a region of significant enrichment for that mark.
Notably, CUTs and SUTs were significantly bound by Pab1, Hrp1, and Nab2 suggesting that 3′ end formation on lncRNAs initially resembles that of mRNAs but culminates in nuclear retention rather than export.
