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Some helicases might function as ssDNA translocases rather than helicases, and self-assembly and/or interactions with accessory proteins are required to activate helicase activity [ 98].
Very little is known about the regulation of acyl-CoA synthetase activities that are required to activate free FAs (Black and Dirusso 2007), and it can only be speculated that glycolysis derived glycerol-3-phosphate or DHAP are the limiting compounds that determine cellular TAG levels in the presence of a surplus of exogenous FAs.
Free activator BH3-only proteins are required to activate effectors.
The failure of nesprin-2 depleted cells to block mitotic entry may be twofold; due to a failure of ERK1/2 to phosphorylate target proteins that are required to activate G2/M arrest and/or due to the activation of inappropriate ERK target proteins that promote cell cycle progression.
The HSF1 pathway most likely raises the level of intracellular stress necessary for IKK activation and IκBα degradation that are required to activate NF-κB [ 433].
However, no direct interaction has been demonstrated between any identified mechanosensory channel and an extracellular protein or matrix; it is also possible that the sensory transducers are basically stretch-activated channels and that the specialized extracellular and cytoskeletal structures are required to activate the channel indirectly by locally increasing membrane tension.
Rather than activate the phones in the store, buyers are required to activate them via an Internet-connected personal computer.
Consequently, students are required to activate their Columbia email accounts immediately after registering.
Students are required to activate their Columbia University Network ID (UNI) and should follow the Checklist for New Students.
Similar(2)
Tyrosine phosphorylation is required to activate Syk kinase activity and function.
Essentially, greater spreading activation is required to activate words that have lower frequencies, i.e., are further out in the lexical or semantic network.
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CEO of Professional Science Editing for Scientists @ prosciediting.com