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Unfortunately, WGBS is still prohibitively expensive for most laboratories, particularly when many replicates are required; significantly, a high fraction of reads contain no methylated cytosines.
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Now, under Tier 2 of Reg A, only SEC review is required, significantly reducing this administrative burden for businesses.
However, for hybrid electric vehicle (HEV) duty with their extreme rates and continuous PSoC operation, improvements are required to significantly extend service life.
As stated previously in the Introduction, only low volume concentrations of nanoparticles are required to significantly alter the thermal properties of the base fluids.
Moreover, it was determined that extremely low ALA dietary intakes are required to significantly affect brain DHA levels and function, assuming however, that the neurological impairments observed with ALA deficiency are caused by the decrease of DHA in brain [144].
While advancements have been made in stent design, alternative drug strategies are required to significantly benefit patient outcomes.
Calculations based on the size of the targeted LDs and the formed nano-LDs suggest that only a few nano-LD budding events are required to significantly increase the surface tension of the donor LD (Thiam et al., 2013a).
However, contrary to results with diploid pests, fitness costs and incomplete resistance are required to significantly delay the evolution of resistance in haplodiploid and parthenogenetic pests (Crowder and Carrière 2009).
In the prime manufacturing zones, the official minimum wage is at least 65 cents an hour, and employers are required to pay significantly more for overtime.
Subsequences are generated from parsing at key frame-disruption positions and are required to align significantly within any original protein homology.
Especially analysis tasks where many repeated simulations of a network with different parameter values are required can profit significantly from parametric model reduction.
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