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Thus, individual members of the metalloproteinase axis are not necessary for gland development per se, but are required for refining the ductal and branching patterns within the mammary gland.
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Close monitoring is required for refining the efficacy of preclinical testing and ensuring the standardisation and repeatability of studies.
Here, we report that hairy is required for refining the terminal cell fate in the embryonic trachea and that hairy's tracheal function is distinct from its earlier role in embryonic patterning.
Understanding which molecular inputs are required for optimal induction of cytokines upon TLR activation may refine our strategies to manipulate excessive inflammation.
In addition, students' curricula are refined based on skillset needs, which are required for future jobs.
An iterative modification technique is suggested to refine the retrofit design and only a few nonlinear static iterations are required for convergence.
This oxidation-reduction process is usually carried out in a separate furnace to ensure that the final smelter product reaches the level of 99.5percentt copper that is required for electrolytic refining.
For instance, three industrial-scale 56/60" single disk refiners were found to be required for a 2000 ODMT/day facility at the 128 kWh/ODMT refining energy.
Considerable scientific expertise is required for PPP producers to be able to further refine the risk assessment and for the assessment authority bodies to understand the measures involved.
For example, with refining energy consumption at 212 kWh/ODMT, electricity purchases are required at higher enzyme loading because more electricity is required for aeration of on-site cellulase enzyme production tanks.
This suggests that further studies are required to refine the risk factors for an infection caused by a MDR organism presenting to the ED in order to prevent overuse of broad-spectrum antibiotics.
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