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However the trans acting factors that bind the CUG repeats and that are reported to be implicated in DM1 [10] have homologues in Drosophila, like CUG-BP1 [36], hnRNP H [37] whereas the muscleblind gene was first identified in Drosophila [38].
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Overexpression of HDAC1, a member of Class I histone deacetylase is reported to be implicated in breast cancer.
Free radical NO was reported to be implicated in lots of physiological and pathological processes including vasodilation, nonspecific host defense and chronic or acute inflammation.
Among these miRNAs, miR-455 has been reported to be implicated in brown adipocyte differentiation [53], while the functions or targets of the others are not determined yet.
Carcinoembryonic antigen-related cell adhesion molecule1 (CEACAM1) has been reported to be implicated in tumor suppression and cell migration of bladder cancer [31], [32].
In other settings, P.aeruginosa has been reported to be implicated in causing human disease, including chronic granulomatous disease in paediatric patients [46] and as a trigger in cystic fibrosis [47].
SNAP25 was reported to be implicated in neuritogenesis in human neuroblastoma [ 56].
In previous studies, the Ndc80 NUF2 complex has been reported to be implicated in the development of multiple human cancers [ 13– 13].
Such responses have previously been reported to be implicated in tumour development and radiation resistance in human cancers [ 9].
Specifically, galectin-1, galectin-3 and to a lesser extent galectin-8 have been reported to be implicated in glioma malignant progression (Table 1).
Many of the detected genes have been reported to be implicated in carcinogenesis and some modules are involved in known pathways.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com