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In all cases, maximum temperatures are reached within 1 year.
It has an elimination half-life of 1.5 2 h and maximal plasma levels are reached within 30 min after oral administration (Schultz et al, 1981).
The maximal levels in plasma, kidney, spleen, lung, and heart are reached within 45 min, whereas in the case of liver a prolonged absorption phase was observed, with the maximal concentration reached at 8 h.
A new formulation, doxazosin gastrointestinal therapeutic system (GITS), allows slow release of the active agent so therapeutic serum levels are reached within 24 hours, rendering dose adjustment unnecessary and eliminating any first-dose effects.
Using the calibrated transport parameter values, simulations of long-term steady-state leaching to the water table demonstrate that even with such slow degradation rates, steady-state concentrations at most piezometers are reached within ∼ 20 yr.
Compared to RFA, no grounding pads are necessary and a larger area is ablated as higher temperatures are reached within the tumour regardless of tissue electrical conductance.
Similar(29)
A final deal is to be reached within 90 days.
A deal could be reached within two weeks.
The rest will be reached within three years.
The deals were reached within several days of each other.
A constant reformate flow was reached within 35 s.
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