Colour genes are rather well understood in poeciliids (see, e.g., [ 87]), and attempts to identify the molecular basis of trait evolution in P. mexicana ecotypes including genes responsible for colour ornamentation are currently underway [ 88].
Generally, the mechanism competes with other mass transfer mechanisms which have been investigated for a long time and are rather well understood.
As stated by Oehlmann-Schulte and Oehlmann [63] the limited number of examples for EDCs in invertebrates is partially due to the fact that their hormonal systems are rather poorly understood in comparison with vertebrates.
In particular, meso-scale (years to decades) sand exchanges between the shoreface and the shoreline, considered as important on many wave-dominated coasts, are rather poorly understood and difficult to identify.
While the folding mechanisms on the scale of the chromatin fiber are rather well understood [1], [2], the higher-order arrangement of whole chromosomes inside the nucleus remains an open question [3] [5].
While the roles and synergistic actions of classical endoglucanases and cellobiohydrolases in the degradation of cellulose are rather well understood [ 6], several questions and challenges remain.
Aerobic microbial degradation of n-alkanes is known since almost a century (Söhngen 1913), and the mechanisms of degradation, with the enzymes and genes involved, are rather well understood (Berthe-Corti and Fetzner 2002; Head et al. 2006; van Beilen and Funhoff 2007; Wentzel et al. 2007).
The megalithic monuments are rather to be understood as a complex of grandiose manifestations of ideas that could well have been diverse, but among which the cult of the dead, nevertheless, played an important role.
For example, there is dissent about whether they display genuinely autonomous collective intentions or whether the acts of the "collective actor" are rather to be understood as resulting from the mere aggregation of individual intentions, thus signifying individual acts of (mis)recognition.
I don't want kids to think their situation defines who they are, rather have them understand that their decision can change their situation.
