Corals harboring thermally sensitive symbionts are rapidly selected out of the gene pool through elevated temperature anomalies [63].
Because of the increasingly female-biased sex ratio in the population during a spreading PI- Wolbachia infection, sex allocation alleles in the host that cause the production of more sons are rapidly selected.
The first is a hitchhiking effect (also known as a selective sweep), in which an entire haplotype with an advantageous variant is rapidly selected to high frequency or even fixation [ 8, 15], leading to a high degree of LD carried by the selected haplotype.
SP-resistant haplotypes were rapidly selected for and fixed in P. falciparum populations infecting pregnant women while SP was widely deployed in Malawi.
Short peptides can now be rapidly selected, which exhibit the same, or higher, specificity and affinity for a defined target molecule, than (say) an antibody or even the natural ligand.
A safety corridor can be rapidly selected and workers in the field can clear the selected route.
Peptides can be rapidly selected from microarrays and covalently conjugated to surfaces for capturing target proteins.
The appropriate peptide ligands have been rapidly selected from high-density arrays and when desirable, the peptide sequences were further optimized by single-point variant screening to enhance both the affinity and activity of the bound enzyme.
In 6 of 8 within-epitope positions where the transmitted virus differed from the B subtype consensus, the B subtype consensus was rapidly selected, suggesting the B-consensus form in these within-epitope positions was a reasonably fit way to impart immune escape (Table S7).
Since we used plaque-purified viruses to infect mice in which the only discernible amino acid in position 627 was glutamic acid, we must conclude that the E627K mutation occurred during infection in mice and that it was rapidly selected out.
In some pathogen host combinations, unnecessary infectivity was rapidly selected against but less so in others.
