Exact(1)
These are proposed to react spontaneously mainly via 1,4-additions with the side chains of lysine, tyrosine, histidine, and cysteine residues, depending on their abundance and accessibility on the target protein, to form covalent protein protein crosslinks (Bittner 2006).
Similar(59)
Like artemisinin and its derivatives, ozonides have been proposed to react with Fe2+ in the parasite to produce free radicals leading to alkylation of key parasitic proteins [ 7].
"There are some mechanisms that are proposed to explain how the Earth can react and revive itself in a way," said Bondesan.
Antibodies that react with both DNA and glutamate receptors on neurons are proposed to mediate excitotoxic neuronal cell death.
This comparison, which reflects the linear sequence, is important because measured antibodies targeting bacterial HSP60 have been proposed to cross-react with the human homolog and elicit the autoimmune reaction seen in bacteria-triggered arthritis [ 9, 10, 13].
The α-bromoacryoyl moiety has been proposed to be important since it reacts with GSH, and reactive drug-GSH intermediates may then modify the DNA by mechanisms not yet fully understood (Geroni et al, 2002; Cozzi, 2003).
Active-TLP (A-TLP) bonding using an interlayer containing both melting point depressant (MPD) and active element which can react with ceramic reinforcement is proposed to improve the wettability between the secondary R/M interfaces.
Of the governor's proposed $10 million, $6.875 million has been set aside for capital costs, such as seismic stations, GPS equipment, telemetry and microwave nodes, while $2.241 million is proposed to help educate people on how to properly react to alerts.
Lithium nitride (Li3N), the only stable alkali metal nitride that reacts readily with CO2, has been proposed to use as a means to break down CO2.
Inactivation by high concentrations of H2O2 is proposed to occur via the generation of reactive oxidants when H2O2 reacts with Compound III.
The methyl radical is proposed to abstract a hydrogen atom from CoBSH to generate a CoBS radical that reacts with bound CoM to generate NiII and the same CoBS−SCoM radical anion proposed in mechanism 1.
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